Publications
Seeking Recyclable Closure for Paper Beverage Bottles |
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We are seeking technologies for a re-closable fiber-based closure for a paper beverage bottle that can be recycled in the paper stream. |
Seeking natural colors for foods and beverages |
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PepsiCo is evaluating different natural color ingredients and technologies to replace Yellow #5, Yellow #6, Red #40, and Blue #1 for multiple food and beverage brands in order to address consumer demand. Specific challenges are in the Red #40 (food) and Blue #1 (food & beverage) replacers. |
Seeking technologies to reduce GHGs in all aspects of the supply chain and manufacturing process. |
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PepsiCo is committed to reducing GHG emissions from seed to shelf. We are looking to engage with partners who can assist us in our goal of reducing GHG 20% by 2030 and achieving net-zero emissions by 2050. As new technologies emerge, efficiencies will be gained and PepsiCo aims to remain at the forefront of best practices in the food and beverage industry. PepsiCo is seeking technologies to reduce GHGs in all aspects of the supply chain and manufacturing process. Solutions may be in one or more of the following areas: • Agriculture – sustainable farming and the reduction of GHG intensive fertilizers • Manufacturing – adopting energy efficient manufacturing processes; novel methods for utilizing waste; use of renewable thermal energy at scale • Packaging – alternative packaging materials and formats that reduce GHGs • Distribution – technologies to assist in the efficiency of our company-owned and third party fleet |
Smart-LEZ : Secure and anonymous vehicle access control solution to traffic-restricted urban areas. |
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The solution proposed uses innovative communication protocols for vehicles and cities: this is a safe and reliable easy-to-use access control system that guarantees user privacy. Our solution is simpler and more economical compared to other expensive systems based on indiscriminate use of video-cameras recording. This technology conciliates efficiency and privacy. |
Exon skipping by CRISPR-Cas9 editing for Duchenne muscular dystrophy |
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Background Duchenne muscular dystrophy (DMD) is a rare, severe genetic disease characterized by progressive muscle wasting. It is caused by mutations in DMD gene that prevent the production of the muscle isoform of dystrophin protein. The symptom onset is usually in early childhood and life expectancy is ~30 years. Elevidys is currently the only gene therapy approved for DMD, which is designed to deliver a gene coding for a shorter version of dystrophin. This approach was taken because delivery of the whole DMD gene is challenging as it is the largest human gene. Antisense oligonucleotide medications for exon skipping (exons 45, 51, and 53) to produce a shorter yet functional dystrophin gene have been approved, which require periodic administration. None of the drugs is suitable for all DMD patients. More treatment solutions are urgently needed. |
Histone Deacetylases (HDAC) Targeted Libraries. Screening compounds for epigenetic drug discovery. |
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The design of selective #HDACs inhibitors requires more exploration due to the multifunctional mechanistic nature of cancer and still remains a great challenge. Dedicating to this promising class of epigenetic anti-cancer drug targets, HDACs Targeted Library (https://bit.ly/3xdJLWw) were kindly prepared by Otava scientists. |
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